This episode, we have two really interesting and very different interviews. Physician’s Weekly speaks with our regular contributor, a registered physician and medical malpractice attorney, who goes by the alias Dr. MedLaw. We explore when and how it is appropriate for physicians to apologize… or not.
But first, Princeton University Professor Rebecca Burdine, PhD, speaks about the value of modelling rare diseases. Dr. Burdine uses small zebrafish for her studies, and you would be amazed at how well these small fish can model diseases, and even be used in diagnostics. Dr. Burdine is also a caregiver to her daughter, who has the rare disease Angelman Syndrome, which Dr. Burdine just happens to study. She provides excellent insights into the value of studying rare diseases.
Willgoss T, Cassater D, Connor S, Krishnan ML, Miller MT, Dias-Barbosa C, Phillips D, McCormack J, Bird LM, Burdine RD, Claridge S, Bichell TJ. Measuring What Matters to Individuals with Angelman Syndrome and Their Families: Development of a Patient-Centered Disease Concept Model. Child Psychiatry Hum Dev. 2021 Aug;52(4):654-668.
Cheng KC, Burdine RD, Dickinson ME, Ekker SC, Lin AY, Lloyd KCK, Lutz CM, MacRae CA, Morrison JH, O'Connor DH, Postlethwait JH, Rogers CD, Sanchez S, Simpson JH, Talbot WS, Wallace DC, Weimer JM, Bellen HJ. Promoting validation and cross-phylogenetic integration in model organism research. Dis Model Mech. 2022 Sep 1;15(9):dmm049600.
Bird LM, Ochoa-Lubinoff C, Tan WH, Heimer G, Melmed RD, Rakhit A, Visootsak J, During MJ, Holcroft C, Burdine RD, Kolevzon A, Thibert RL. The STARS Phase 2 Study: A Randomized Controlled Trial of Gaboxadol in Angelman Syndrome. Neurology. 2021 Feb 16;96(7):e1024-e1035.
Patterson VL, Burdine RD. Swimming toward solutions: Using fish and frogs as models for understanding RASopathies. Birth Defects Res. 2020 Jun;112(10):749-765.
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